STAGE III RENAL CELL CANCER AJCC V8
Clinical trials for STAGE III RENAL CELL CANCER AJCC V8 explained in plain language.
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Virus-Immunotherapy combo shows promise in kidney cancer trial
Disease control Not yet recruitingThis study tests whether adding a lab-modified virus (VSV-IFNβ-NIS) to standard immunotherapy drugs (ipilimumab and nivolumab) can shrink tumors in people with advanced or metastatic clear cell renal cell carcinoma. The virus is designed to kill cancer cells without harming norma…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 10:40 UTC
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Could a smaller dose of this cancer drug work just as well?
Disease control Not yet recruitingThis study tests whether giving a lower dose of the immunotherapy drug nivolumab less often can still control advanced cancers that have spread or can't be removed surgically. The goal is to make treatment more affordable and accessible worldwide. About 50 adults with various can…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Cold sore virus modified to fight kidney cancer in new trial
Disease control Not yet recruitingThis study tests a new treatment for advanced kidney cancer that has spread and worsened after immunotherapy. The treatment combines a modified cold sore virus (RP2) that attacks tumor cells and activates the immune system, with a targeted drug (tivozanib) that blocks tumor growt…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New drug combo aims to shrink kidney tumors before surgery
Disease control Not yet recruitingThis early-phase trial tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery is safe and helps shrink high-risk kidney cancers that haven't spread. About 16 adults with clear cell renal cell carcinoma will receive the drugs, then have their ki…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Gut bacteria may supercharge immunotherapy in kidney cancer trial
Disease control Not yet recruitingThis phase III trial tests whether adding a live biotherapy called MO-03 to standard immunotherapy can help control advanced or metastatic clear cell renal cell carcinoma. MO-03 is designed to improve gut health, which may make immunotherapy work better. About 718 participants wi…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 12, 2026 13:40 UTC