New drug combo aims to shrink kidney tumors before surgery

NCT ID NCT07516366

First seen Apr 19, 2026 · Last updated May 13, 2026 · Updated 2 times

Summary

This early-phase trial tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery is safe and helps shrink high-risk kidney cancers that haven't spread. About 16 adults with clear cell renal cell carcinoma will receive the drugs, then have their kidney tumor removed. The goal is to see if this approach can improve outcomes without causing major delays or side effects.

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