STAGE II LUNG CANCER AJCC V8

This study tests a two-step treatment for people with stage II or III non-small cell lung cancer who are not healthy enough for surgery. First, they receive a shorter, higher-dose course of radiation. Then they get an immunotherapy drug called atezolizumab to help their immune sy…

This study tests whether adding an immunotherapy drug called atezolizumab to standard radiation therapy helps people with early-stage non-small cell lung cancer live longer. About 415 participants with stage I-IIA lung cancer will receive either radiation alone or radiation plus …

This study tests whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with limited stage small cell lung cancer live longer. About 544 participants will receive either chemoradiation alone or chemoradiation plus atezolizumab. The goal is to s…

This study is for people with non-small cell lung cancer who have had chemotherapy and surgery. It tests whether adding a drug called AZD6738 to the immunotherapy drug durvalumab can help keep the cancer from coming back longer than durvalumab alone. About 630 adults with stage I…

This early-phase trial studies the safety and effectiveness of combining two immunotherapy drugs (ipilimumab and nivolumab) with radiation therapy for patients with stage II or III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this combinatio…

This study tests whether a lung cancer drug called atezolizumab can be safely given as a shot under the skin at home, with doctors monitoring patients through video calls. It involves 5 adults with non-small cell lung cancer. The goal is to see if this home-based approach is prac…

This study compares two treatments for lung tumors: microwave ablation (using heat to kill cancer cells) and surgical wedge resection (removing a small piece of lung). It includes adults with non-small cell lung cancer, sarcoma, or colorectal cancer that has spread to the lungs. …

This early-stage trial tests a drug called NBTXR3 that makes radiation more effective at killing cancer cells. It is for people with non-small cell lung cancer that has returned and cannot be removed with surgery. The study aims to find the safest dose and see if combining the dr…

This study tests an online program designed to help women with lung cancer feel more supported and less distressed during treatment. The program uses techniques like mindfulness and emotional processing to improve social well-being. About 70 women with stage I-IV non-small cell l…

This study looks at whether updating radiation treatment plans at set times (adaptive planning) can lower side effects like lung inflammation in people with stage II-IV non-small cell lung cancer. About 34 participants will receive standard radiation and immunotherapy, but their …

This study tests a telehealth self-management program for people who have finished treatment for early-stage lung or colorectal cancer. The program provides coaching on follow-up care, communication with doctors, and quality of life. Researchers will compare outcomes between part…

This study is testing a low-literacy conversation tool designed to help people with lung cancer and their doctors make treatment decisions together. About 98 adults with non-small cell lung cancer will use the tool and report on their anxiety, decision confidence, and satisfactio…

This study aims to find out why some cancer patients develop nerve damage (tingling or numbness in hands and feet) from taxane chemotherapy. Researchers will track over 1,300 people with breast, lung, or ovarian cancer to see how age, gender, and other factors affect their risk. …