STAGE I LUNG CANCER AJCC V8

This study is testing whether artificial intelligence (AI) can help doctors choose the right radiation dose for people with lung cancer or tumors that have spread to the lung. The treatment uses a precise type of radiation called SBRT, and the AI aims to personalize the dose to e…

This study tests whether the drug canakinumab can prevent lung cancer in 50 people who have suspicious lung nodules that haven't gone away. Participants receive the drug and are monitored for nodule shrinkage and cancer development. The goal is to see if this approach can stop lu…

This study tests whether a home-based breathing exercise program can help people who have finished treatment for early-stage lung cancer (stages I-III) breathe easier, feel less tired, and stay more active. About 100 survivors will do breathing exercises at home for several weeks…

This phase 2 trial tests whether doing special breathing exercises (respiratory muscle training) for a few weeks before lung cancer surgery can reduce serious lung complications like pneumonia and breathing trouble. About 220 people with stage I-IIIB lung cancer will either do th…

This study tests whether a yoga program designed for both patients and their family caregivers can improve physical function, fatigue, sleep, mood, and quality of life. It includes 400 people with lung or esophageal cancer who are getting radiation therapy, plus their caregivers.…

This study looks at how the bacteria in your gut might cause stomach issues like diarrhea and colitis when you take certain cancer drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or g…

This trial compares two standard surgical techniques for early-stage lung cancer: tying off the pulmonary vein first versus the pulmonary artery first. Researchers want to see which method better reduces circulating tumor DNA (ctDNA) in the blood after surgery, as lower ctDNA may…

This study looks at whether giving early-stage lung cancer patients detailed information about quality of life outcomes helps them feel more satisfied with their choice between surgery and radiation therapy. About 150 patients will be enrolled, and researchers will measure decisi…