ST-ELEVATION MYOCARDIAL INFARCTION

This study compares a new approach using fewer stents and a drug-coated balloon to the standard method of placing stents in heart attack patients. About 1,272 participants will be randomly assigned to one of the two treatments. The goal is to see if the reduced-stent strategy low…

This study tests using a drug-coated balloon instead of a permanent stent to open blocked arteries during a heart attack. The balloon delivers medication to prevent re-blockage without leaving a metal implant. Researchers will track 300 participants to see if this approach is saf…

This study looks at 350 heart attack patients who get a special stent and then take only a strong blood thinner (no aspirin) for a year. The goal is to see if this approach lowers bleeding risk as much as the standard aspirin-plus-blood-thinner combo, while still preventing futur…

This study tests if dapagliflozin, a drug used for diabetes, can reduce heart muscle damage in people having a severe heart attack (STEMI). About 256 participants will receive either the drug or a placebo right before a procedure to open blocked arteries. The main goal is to see …

This study looks at a special balloon coated with a drug (sirolimus) that is inflated inside blocked heart arteries to open them and prevent reclogging. About 1,100 adults with various types of coronary artery disease will be treated and followed for up to 3 years. The goal is to…

This study tests an experimental drug called RTP-026 in people who have had a severe type of heart attack (STEMI). The goal is to see if the drug is safe and can reduce heart muscle damage when given alongside standard emergency treatment. About 96 adults will participate, and ha…

This study tests two methods used during emergency heart attack treatment: ischemic postconditioning (briefly pausing blood flow after opening the artery) and ultrasound-guided stent placement. The goal is to see if these techniques reduce death, heart failure, or the need for an…

This study explores a new blood test that looks for DNA fragments from damaged heart cells to detect active heart inflammation in people with sarcoidosis. Researchers will compare results from 120 participants, including healthy volunteers and those with known heart conditions. I…

This study will follow 20,000 people who had a heart attack and were sent home early from the hospital. Researchers want to see how well their medications are working, track any new heart problems, and measure their quality of life after one year. No new treatment is being tested…

This study compares two ways to guide heart artery opening procedures in 1500 people who had a major heart attack. One method uses standard X-ray dye pictures (angiography), and the other uses a more detailed light-based camera (optical coherence tomography). The goal is to see i…

This study looks at people who had a major heart attack (STEMI) and have other narrowed arteries that did not cause the attack. Doctors want to learn which of these other narrowings are likely to cause future problems, like another heart attack or chest pain. Using CT scans and b…