SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Clinical trials for SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX explained in plain language.
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MRI-Guided radiation boost shows promise in head and neck cancer trial
Disease control OngoingThis study tests whether giving an extra dose of radiation to oxygen-poor (hypoxic) areas of head and neck tumors can improve treatment response. About 91 adults with advanced squamous cell cancer of the throat or voice box will receive standard chemo-radiation with or without th…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Phase: PHASE2 • Sponsor: Regina Elena Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Can less radiation be just as good for HPV throat cancer?
Disease control OngoingThis study looks at whether giving less radiation after surgery for HPV-positive throat cancer can still prevent the cancer from coming back while causing fewer long-term side effects. About 83 adults with HPV-positive oropharyngeal cancer will receive either a standard or reduce…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Phase: NA • Sponsor: Indiana University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Could fewer radiation sessions after surgery improve quality of life for head and neck cancer patients?
Disease control OngoingThis study tests a shorter, more intense course of radiation therapy (hypofractionated IMRT) given after surgery for head and neck cancer. The goal is to see if it is safe and if it can help patients maintain better swallowing function compared to the standard longer radiation sc…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug shows promise in shrinking head and neck tumors before surgery
Disease control OngoingThis study tests an oral drug called APG-157 given before standard treatment (surgery or radiation) for people with newly diagnosed head and neck cancer. The goal is to see if the drug can shrink tumors and improve outcomes. About 24 adults with early to advanced stage cancer wil…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Phase: PHASE2 • Sponsor: Aveta Biomics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Surgical sleuthing: new method hunts for hidden cancer origins
Diagnosis OngoingThis study tests a surgical technique called tongue base mucosectomy, combined with detailed tissue analysis, to find the original site of head and neck cancers that have spread to lymph nodes but have no known primary source. About 100 patients will undergo this procedure, and r…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Sponsor: Royal Marsden NHS Foundation Trust • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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New drug aims to spare cancer patients from debilitating mouth sores
Symptom relief OngoingThis phase 2 trial tests whether the drug RRx-001 can prevent severe oral mucositis (painful mouth sores) in 216 patients with head and neck cancer receiving standard chemoradiation. Patients are randomly assigned to receive RRx-001 or a placebo alongside their usual treatment. T…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE OROPHARYNX
Phase: PHASE2 • Sponsor: EpicentRx, Inc. • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC