Experimental drug aims to shrink head and neck cancers before surgery

NCT ID NCT05312710

First seen Jan 17, 2026 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tests an oral drug called APG-157 in 24 people with newly diagnosed head and neck cancer. The goal is to see if taking the drug before standard treatments like surgery can shrink tumors and improve outcomes. Researchers will measure tumor size changes using scans and check immune markers in biopsies.

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Contacts and locations

Locations

  • University of Miami Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • VAGLAHS, West Los Angeles

    Los Angeles, California, 90073, United States

Conditions

Explore the condition pages connected to this study.