SMALL BOWEL ADENOCARCINOMA

This early-phase trial tests a two-vaccine strategy in 18 adults with advanced colorectal or small bowel cancer that has not responded to standard treatments. The first vaccine is given as a shot, followed by two doses of a second vaccine given through a vein. The goal is to find…

This study tests a combination of four chemotherapy drugs (NALIRIFOX) in people with advanced small bowel cancer that cannot be removed by surgery. The goal is to see how well the treatment shrinks tumors and controls the disease. About 36 adults will receive the drugs through an…

This study tests whether the immunotherapy drug dostarlimab works better than standard chemotherapy as the first treatment for people with advanced cancers that have specific genetic markers (dMMR/MSI). The cancers studied are rare types like pancreatic, stomach, and small bowel …

This study reviews past medical records of 400 people with Lynch syndrome who had a small bowel capsule endoscopy (a camera in a pill) to screen for early growths or cancer. The goal is to see how well this test finds precancerous or cancerous lesions in the small bowel. Results …

This study looks at how well a tiny camera you swallow (videocapsule endoscopy) can find early signs of small bowel cancer in people with Lynch syndrome. About 100 adults with Lynch syndrome will swallow the camera pill as part of their regular care. Researchers will track how ma…