SICKLE CELL DISEASE (SCD)
Clinical trials for SICKLE CELL DISEASE (SCD) explained in plain language.
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Can gene therapy free sickle cell patients from painful crises?
Disease control Not yet recruitingThis trial compares a new gene therapy to standard care in people aged 12 to 35 with severe sickle cell disease. The gene therapy uses a patient's own blood stem cells, modified to produce a therapeutic form of hemoglobin and reduce the sickling hemoglobin. The study measures how…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Simple breathing device may speed recovery from a deadly sickle cell complication
Disease control Not yet recruitingThis trial investigates whether continuous positive airway pressure (CPAP) can help adults with sickle cell disease recover faster from acute chest syndrome, a serious lung complication. Participants who need extra oxygen are randomly assigned to receive either standard oxygen al…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Early screening and care for sickle cell in newborns could save lives
Disease control Not yet recruitingThis study will test 120 babies in Côte d'Ivoire for sickle cell disease using a simple point-of-care test. Babies who test positive will start comprehensive care early, including medicines and vaccines. Researchers want to see if this approach reduces serious health problems and…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: PHASE4 • Sponsor: Swiss Tropical & Public Health Institute • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could ketamine beat opioids for sickle cell pain in kids?
Symptom relief Not yet recruitingThis study tests whether a low-dose ketamine injection can relieve pain in children with sickle cell disease during a pain crisis better than standard opioid medications. Researchers will compare how quickly pain improves and whether fewer children need to be admitted to the hosp…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: PHASE4 • Sponsor: University of Mississippi Medical Center • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Could a simple seed ease sickle cell pain? new study hopes to find out
Symptom relief Not yet recruitingThis study will test whether eating flaxseed, a source of omega-3 fatty acids, can help reduce pain and improve daily life for children with sickle cell disease. Twenty children aged 5 to 18 will take part. The main goal is to see if it's possible for them to eat flaxseed regular…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New study aims to track dangerous infections in kids with sickle cell disease
Knowledge-focused Not yet recruitingThis study will look at medical records of 350 children with sickle cell disease in France who had serious bacterial infections between 2020 and 2025. The goal is to find out which bacteria are causing these infections today, especially with new vaccines available. The results co…
Matched conditions: SICKLE CELL DISEASE (SCD)
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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Can a 90-Minute training improve care for kids with sickle cell?
Knowledge-focused Not yet recruitingThis study tests a 90-minute virtual training for healthcare providers that teaches them to see each patient's unique perspective and communicate more clearly. The goal is to improve how doctors talk to children with sickle cell disease. Thirty providers from three hospitals will…
Matched conditions: SICKLE CELL DISEASE (SCD)
Phase: NA • Sponsor: Connecticut Children's Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC