New study aims to track dangerous infections in kids with sickle cell disease

NCT ID NCT07639008

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will look at medical records of 350 children with sickle cell disease in France who had serious bacterial infections between 2020 and 2025. The goal is to find out which bacteria are causing these infections today, especially with new vaccines available. The results could help improve prevention and treatment for these children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand which bacteria cause serious infections in children with sickle cell disease, leading to improved vaccines and prevention plans.
What could go wrong: This is an observational study that only looks at past data, so it cannot test new treatments or prove what works best. The findings may not apply to children outside France.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INVASIVE BACTERIAL INFECTIONS SICKLE CELL DISEASE (SCD)

Contacts and locations

Locations

CH Gonesse

Gonesse, France
CH Rambouillet

Rambouillet, France
CH Rives de Seine, Site de Neuilly-sur-Seine

Neuilly-sur-Seine, France
CH Saint Denis, Hôpital Delafontaine

Saint-Denis, France
CH Sud Francilien

Corbeil-Essonnes, France
CH du Sud Seine et Marne

Fontainebleau, France
CHI Créteil

Créteil, France
CHI Poissy

Poissy, France
CHI Robert Ballanger

Aulnay-sous-Bois, France
CHU Lenval

Nice, France
CHU Nantes

Nantes, France
GH Sud Ile-de-france

Melun, France
GHEF, Site de Marne-la-Vallée

Jossigny, France
GHEF, Site de Meaux

Meaux, France
GHI Le Raincy-Montfermeil

Montfermeil, France
GHT Yvelines Nord

Mantes-la-Jolie, France
Hôpital Ambroise Paré

Boulogne-Billancourt, France
Hôpital André Mignot

Versailles, France
Hôpital Antoine Béclère

Clamart, France
Hôpital Bicêtre

Le Kremlin-Bicêtre, France
Hôpital Intercommunal Villeneuve-St-Georges

Villeneuve-Saint-Georges, France
Hôpital Jean Verdier

Bondy, France
Hôpital NOVO

Cergy-Pontoise, France
Hôpital Necker

Paris, France
Hôpital Nord, AP-HM

Marseille, France
Hôpital Paris-Saclay

Orsay, France
Hôpital Pellegrin - Hôpital des Enfants

Bordeaux, France
Hôpital Robert Debré

Paris, France
Hôpital Saint Camille

Bry-sur-Marne, France
Hôpital Trousseau

Paris, France
Hôpital Victor Dupouy (CH Argenteuil)

Argenteuil, France

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