SICKLE CELL DISEASE
Clinical trials for SICKLE CELL DISEASE explained in plain language.
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Sickle cell drug voxelotor safety check ends early
Disease control TerminatedThis study looked at the long-term safety of the drug voxelotor in 162 people with sickle cell disease who had already taken it in earlier studies. The main goal was to track any side effects. The study was stopped early, but the results help doctors understand how safe voxelotor…
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 17, 2026 00:01 UTC
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Sickle cell drug trial for kids halted early – but data may still help
Disease control TerminatedThis study tested a drug called voxelotor in children aged 2 to 15 with sickle cell disease who had slightly abnormal blood flow in the brain. The goal was to see if the drug could improve blood flow and reduce stroke risk. The trial was stopped early, but the results may still p…
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 16, 2026 23:59 UTC
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Could a cancer drug tame sickle cell pain?
Disease control TerminatedThis early-phase study tested the drug imatinib in 7 people with sickle cell anemia who have frequent pain crises. The goal was to see if imatinib could reduce harmful changes in red blood cells and lower the number of severe pain episodes. The study was stopped early, so results…
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Indiana University • Aim: Disease control
Last updated May 16, 2026 23:59 UTC
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Sickle cell drug voxelotor tested for Long-Term safety in extension study
Disease control TerminatedThis study looked at the long-term safety of the drug voxelotor in people with sickle cell disease who had already taken it in a previous study. About 179 participants were enrolled to track side effects and complications like pain crises. The study was terminated early, but the …
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 16, 2026 23:58 UTC
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Sickle cell drug inclacumab safety checked in long-term study
Disease control TerminatedThis study looks at the long-term safety of inclacumab in people with sickle cell disease who have already taken the drug in a previous study. It tracks side effects and how often pain crises happen. The goal is to see if the drug remains safe over time.
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 16, 2026 23:54 UTC
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Gene-Editing hope for sickle cell patients, but trial halted early
Disease control TerminatedThis early-stage study tested a gene-edited stem cell treatment (OTQ923) in 4 people with severe sickle cell disease. The goal was to boost fetal hemoglobin to reduce painful crises and other complications. The trial was terminated early, so full results are limited, but it aimed…
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Sickle cell drug safety study ends early
Disease control TerminatedThis study was designed to check the long-term safety of the drug GBT021601 in people with sickle cell disease who had already taken it in a previous study. It included 47 participants aged 6 months and older. The study was terminated early, so results are limited.
Matched conditions: SICKLE CELL DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Sickle cell drug oxbryta under the microscope: 5-Year registry reveals Real-World impact
Disease control TerminatedThis study followed 265 people with sickle cell disease who were taking Oxbryta to see how the drug worked in everyday life, outside of a controlled trial. Researchers tracked changes in blood counts, organ function, and complications like pain crises over up to 5 years. The goal…
Matched conditions: SICKLE CELL DISEASE
Sponsor: Pfizer • Aim: Disease control
Last updated May 05, 2026 11:55 UTC