Cancer drug may tame sickle cell pain, early study hints
NCT ID NCT03997903
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study tested whether imatinib, a drug used for certain cancers, could reduce painful blockages in blood vessels (vaso-occlusive crises) in people with sickle cell anemia. Seven participants aged 18–25 took the drug for 6 months while researchers measured changes in red blood cell health and pain episodes. The study was terminated early, so results are limited.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cincinnati Children's Hospital
Cincinnati, Ohio, 45229, United States
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Riley Hospital for Children at IU Health
Indianapolis, Indiana, 46202, United States