SEZARY SYNDROME
Clinical trials for SEZARY SYNDROME explained in plain language.
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Combination therapy aims to boost response in rare skin cancers
Disease control Recruiting nowThis trial tests whether combining the drug mogamulizumab with low-dose total skin electron beam therapy works better than either alone for people with mycosis fungoides or Sezary syndrome, two rare types of skin lymphoma. Participants receive both treatments over several weeks. …
Matched conditions: SEZARY SYNDROME
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Jul 01, 2026 23:00 UTC
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Immunotherapy and chemo join forces against tough lymphoma
Disease control Recruiting nowThis study tests two drugs—durvalumab (an immunotherapy) and lenalidomide (a chemotherapy drug)—alone or together in people with T-cell lymphoma that has returned or not responded to prior treatment. The goal is to find the best dose and see how well the combination works. About …
Matched conditions: SEZARY SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a lower dose of this cancer drug be just as good?
Disease control Recruiting nowThis study is testing whether a lower dose of the drug brentuximab vedotin can still effectively treat three types of skin lymphoma: mycosis fungoides, Sezary syndrome, and lymphomatoid papulosis. The goal is to see if reducing the dose can maintain benefits while possibly loweri…
Matched conditions: SEZARY SYNDROME
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Can a light therapy clean cancer cells from blood? new trial aims to find out
Disease control Recruiting nowThis phase 2 trial is testing whether a procedure called extracorporeal photopheresis (ECP) can reduce tumor cells in people with Sezary syndrome, a rare blood cancer that affects the skin. Twenty participants will receive ECP weekly for a month, then every two weeks for five mon…
Matched conditions: SEZARY SYNDROME
Sponsor: Oleg E. Akilov, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New combo therapy hopes to tackle rare skin cancer
Disease control Recruiting nowThis phase II trial tests whether combining a targeted antibody drug (mogamulizumab) with a procedure that treats white blood cells with light (extracorporeal photopheresis) can better control erythrodermic cutaneous T-cell lymphoma, a rare skin cancer. About 34 adults with advan…
Matched conditions: SEZARY SYNDROME
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New drug shows promise for rare skin cancers
Disease control Recruiting nowThis study is tracking how safe and effective the drug mogamulizumab (Poteligeo) is for adults with two rare types of skin lymphoma: mycosis fungoides and Sézary syndrome. Researchers will monitor 15 participants in routine care settings for side effects and how well the drug con…
Matched conditions: SEZARY SYNDROME
Sponsor: Kyowa Kirin Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Massive T-Cell lymphoma database aims to unlock new insights
Knowledge-focused Recruiting nowThis study is creating a large database of information and tissue samples from 1,000 people with T-cell lymphoma. Researchers will use this data to learn more about the disease and how to improve patient outcomes. Participants provide medical information and optional blood and na…
Matched conditions: SEZARY SYNDROME
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Scientists seek skin and blood samples to unlock secrets of rare lymphoma and common eczema
Knowledge-focused Recruiting nowThis study collects blood, urine, and skin samples from 200 adults with cutaneous T-cell lymphoma, eczema, or atopic dermatitis. The samples are stored and used for current and future research, such as studying proteins in the blood and tissue. Participants must have one of these…
Matched conditions: SEZARY SYNDROME
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC