Could a lower dose of this cancer drug be just as good?
NCT ID NCT03587844
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a lower dose of the drug brentuximab vedotin can still effectively treat three types of skin lymphoma: mycosis fungoides, Sezary syndrome, and lymphomatoid papulosis. The goal is to see if reducing the dose can maintain benefits while possibly lowering side effects. About 58 adults with these conditions are being enrolled to compare different dosing schedules.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
brentuximab vedotin
What this could lead to
If successful, this could show that a lower dose of brentuximab vedotin is still effective for these skin lymphomas while causing fewer side effects.
What could go wrong
This is a small Phase 2 trial with only 58 participants, so results may not apply to everyone. Lower doses might also be less effective at controlling the disease.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Memorial Sloan Kettering Basking Ridge
RECRUITINGBasking Ridge, New Jersey, 07920, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Bergen
RECRUITINGMontvale, New Jersey, 07645, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-••••
Contact
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Commack
RECRUITINGCommack, New York, 11725, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Monmouth
RECRUITINGMiddletown, New Jersey, 07748, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Nassau
RECRUITINGUniondale, New York, 11553, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Westchester
RECRUITINGEast White Plains, New York, 10604, United States
Contact Phone: •••-•••-••••
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Stanford University Medical Center
RECRUITINGStanford, California, 94305-5408, United States
Contact Phone: •••-•••-••••