SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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New hope for MS patients: ofatumumab cuts relapses in switchers
Disease control CompletedThis study looked at how well ofatumumab works in 562 people with relapsing multiple sclerosis who switched from other drugs (fumarates or fingolimod) because their disease was still active. The main goal was to see how many relapses they had per year. Researchers also tracked si…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Gold nanoparticles tested as brain energy boost for MS
Disease control CompletedThis phase 2 trial tested a liquid suspension of gold nanocrystals, called CNM-Au8, in 33 people with relapsing multiple sclerosis. The goal was to see if the treatment could improve energy metabolism in brain cells, measured by a special MRI scan. Participants took the drug by m…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Clene Nanomedicine • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Eye camera spots hidden inflammation in MS patients
Knowledge-focused CompletedThis study used a special eye camera (adaptive optics) to look at blood vessel inflammation in the retina of 50 people with multiple sclerosis (MS) and healthy volunteers. The goal was to see if this inflammation differs between MS types and could serve as an early marker of dise…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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MS drug safety survey: do patients and doctors know the risks?
Knowledge-focused CompletedThis completed survey looked at whether healthcare professionals and people with multiple sclerosis (or their caregivers) understand the safety steps needed when using the drug Mayzent (siponimod). Over 300 participants from Europe answered questions about proper use, side effect…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Real-World study reveals siponimod use in russian MS patients
Knowledge-focused CompletedThis study looked back at medical records of 606 people with secondary progressive multiple sclerosis (SPMS) in Russia who were taking siponimod. Researchers wanted to understand patient characteristics and how the drug was used in everyday practice. The study collected data from…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:18 UTC