SAFETY ISSUES

This study is checking how safe and well-tolerated the diabetes drug empagliflozin (taken with or without metformin) is in Pakistani adults with type 2 diabetes. About 2000 people aged 18-65 with poorly controlled blood sugar will be followed for 6 months. The study will track si…

This early-phase trial tests an experimental oral drug called IPG7236 in people with advanced solid tumors that have spread or cannot be removed. The study has two parts: first, finding a safe dose, then expanding to see if the drug can control tumor growth. About 196 participant…

This study tests whether a brief counseling program called BeSMART, given to parents while their child is in the hospital, can improve how they store firearms at home. About 400 caregivers of hospitalized children will be randomly assigned to receive the counseling or usual care.…

This early-stage study tests a single dose of SSS55 injection in 26 healthy adults in China. The main goal is to check if it is safe and how the body handles it. Researchers will also look at how it affects the immune system. This is a first step before testing it in people with …

This study is tracking 400 people with acute or subacute blood clots in their legs to see how well endovascular treatments (minimally invasive procedures using catheters, balloons, stents, or clot-removal devices) work. The main goal is to see how many patients avoid amputation a…