SAFETY ISSUES
Clinical trials for SAFETY ISSUES explained in plain language.
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New hope for transplant patients with hepatitis b: safer drug switch under study
Disease control OngoingThis study looks at switching kidney or liver transplant patients with chronic hepatitis B to a drug called tenofovir alafenamide (TAF). The goal is to see if TAF is safer for the kidneys, controls the virus well, and is easier for patients to stick with. The study involves 52 ad…
Matched conditions: SAFETY ISSUES
Phase: PHASE4 • Sponsor: Taichung Veterans General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New Gene-Silencing drug takes first step in human safety trial
Disease control OngoingThis early-stage trial is testing a new drug called RG002C0106 in 30 healthy adults to see if it is safe and how the body processes it. The drug uses RNA interference to silence a gene involved in the immune system's complement pathway. The study is randomized and placebo-control…
Matched conditions: SAFETY ISSUES
Phase: PHASE1 • Sponsor: Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Could donor cells boost rotator cuff repair? early trial begins
Disease control ENROLLING_BY_INVITATIONThis early-phase trial tests whether injecting special donor cells (E-CEL UVEC) into the shoulder during rotator cuff surgery is safe and might improve healing. Twenty adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check…
Matched conditions: SAFETY ISSUES
Phase: PHASE1 • Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can training hospital staff on gun safety prevent child shootings?
Prevention ENROLLING_BY_INVITATIONThis study tests a program called ACTFAST that trains doctors and nurses at three children's trauma centers to talk with families about safe firearm storage. The goal is to help prevent gun injuries in kids. Researchers will survey parents, teens, and clinicians to see if the tra…
Matched conditions: SAFETY ISSUES
Phase: NA • Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Jun 27, 2026 11:01 UTC
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Can trauma centers prevent gun injuries? new study aims to find out
Prevention ENROLLING_BY_INVITATIONThis study tests a program called ACTFAST in three trauma centers. The program screens injured patients for firearm access, offers brief counseling on safe storage, and connects them to community resources. Researchers will track whether the program increases safe storage practic…
Matched conditions: SAFETY ISSUES
Phase: NA • Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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First human trial of ETD-001 gel begins safety testing
Knowledge-focused ENROLLING_BY_INVITATIONThis early-stage trial tests the safety and tolerability of ETD-001 gel in healthy Chinese adults aged 18 to 60. Participants receive either the gel or a placebo, with doses increased gradually. The study aims to understand how the body processes the gel and whether it causes any…
Matched conditions: SAFETY ISSUES
Phase: PHASE1 • Sponsor: Etern Therapeutics Wuxi Limited • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC