SAFETY ISSUES

This is an early safety study to see if a new oral drug called ICM20 is safe and tolerable for adults with Chagas disease. It will test ICM20 alone and combined with an existing drug, benznidazole, in 13 participants who have never been treated for Chagas before. The main goal is…

This early-stage study is testing whether adding special lab-grown cells from umbilical cords to standard shoulder surgery is safe and might improve healing. The trial will enroll 20 adults aged 45-70 with full-thickness rotator cuff tears who haven't improved with physical thera…

This study is testing a new hospital program designed to prevent firearm injuries. The program involves training trauma center staff to screen patients for risk and provide safety education. Researchers will measure whether the program changes staff practices and improves patient…

This study aims to prevent firearm injuries by training doctors and staff at three major children's trauma centers to talk with families about gun safety. It will involve up to 1,000 parents and young patients to see if the training helps doctors provide better safety advice and …

This is an early-stage study to check the safety and basic effects of a new injection called RG002C0106 in healthy adults. Researchers will give different doses to small groups of volunteers and compare them to a placebo (dummy shot) to see how the body handles it and if it cause…