SAFETY

This study checks the safety of the Prevenar 20 vaccine after it is already available in Korea. About 660 people aged 6 weeks and older who are prescribed the vaccine will take part. Researchers will track any side effects for 28 days after vaccination.

This early-stage study tests whether a new medicine called GenSci134 is safe and tolerable for people. It involves healthy adults and patients with adult growth hormone deficiency, a condition where the body doesn't make enough growth hormone. Participants receive either the stud…

This study tests a new treatment using stem cells from amniotic membrane for people with calciphylaxis, a rare and painful condition where blood vessels harden and cause severe skin wounds. The treatment is given to 9 adults with chronic kidney disease to see if it helps wounds h…

This study tests an experimental drug called HYP-2090PTSA in people with advanced solid tumors that have a specific genetic change called a KRAS mutation. The goal is to find the safest dose and see if the drug can shrink tumors. About 257 adults will take part in two phases: fir…

This study tests a new drug called AK104 combined with standard chemotherapy and either cetuximab or bevacizumab for people with a specific type of advanced colorectal cancer (MSS type) that has not responded to initial treatment. The goal is to see if this combination can shrink…

This early-stage study tests a single injection of a new drug called GenSci098 in 24 adults with Graves' disease, a condition where the thyroid is overactive. The main goal is to see if the drug is safe and what side effects it might cause. Participants must have stopped other th…

This early-stage study tests whether a single injection of special stem cells (made from reprogrammed human cells) is safe for people with a recent spinal cord injury. About 12 adults with moderate to severe paralysis will receive the cells. The main goal is to check for side eff…

This study tests a new drug called HY07121 in about 258 adults with advanced solid tumors that have not responded to standard treatments. The goal is to check the drug's safety, find the right dose, and see if it can shrink tumors. Participants receive the drug by infusion, and t…

This early-stage study tests the safety of a new drug called GenSci098 in 76 adults with active thyroid eye disease (TED). Participants receive one or more injections under the skin, and researchers monitor for side effects and how the drug moves through the body. The goal is to …

This study tests an experimental drug called IRL757 in people with Parkinson's disease who also experience apathy (loss of interest or motivation). The main goal is to see if the drug is safe and tolerable over 12 weeks. About 75 participants will receive either IRL757 or a place…

This early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can safely reduce demoralization—a deep sense of hopelessness—in 15 adults with advanced cancer. Participants receive 6 therapy sessions plus one 25 mg dose of ps…

This early-stage trial is checking if a single inhaled dose of RCS-21 is safe and tolerable in 24 healthy adults aged 18 to 64. Participants receive one dose and are closely monitored for side effects. The study does not aim to treat any disease, just to gather initial safety and…

This study is checking if taking a supplement called palmitoylethanolamide (PEA) every day for a year is safe for healthy adults. About 200 people aged 18 and older will take either PEA or a placebo pill, and researchers will track any side effects. The goal is to see if long-ter…

This early-stage study tests a new antibiotic combination (ceftibuten-ledaborbactam etzadroxil) in about 46 healthy adults aged 18-55. The goal is to check safety and how the drug moves through the body, not to treat any disease. Results will help decide if further studies are po…

This study tests whether taking curcumin (a compound in turmeric) for two weeks can cross into the brain and attach to amyloid-beta proteins, which are linked to Alzheimer's disease. Researchers will use eye imaging to see if these proteins become visible, and also check how curc…

This study surveys 400 doctors, nurses, and respiratory therapists worldwide to understand how non-invasive ventilation (breathing support via mask or helmet) is used outside intensive care units. The goal is to identify current practices, outcomes, and challenges to make this tr…