RUMINATION
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Can a common drug stop the spiral of negative thoughts in depression?
Symptom relief OngoingThis study tests whether adding aripiprazole to a standard antidepressant (escitalopram) can reduce repetitive, intrusive negative thinking (rumination) in people with major depression. About 108 adults with depression and high rumination will receive either escitalopram alone or…
Matched conditions: RUMINATION
Phase: NA • Sponsor: Central South University • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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Pen and paper power: journaling may supercharge psychotherapy
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether adding a structured therapy journal to standard cognitive behavioral therapy (CBT) helps people with mental health conditions like depression, anxiety, or eating disorders feel better faster. About 80 adults in outpatient CBT will be randomly assigned …
Matched conditions: RUMINATION
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated May 08, 2026 12:04 UTC