RHEUMATOID ARTHRITIS (RA)

This Phase 1 study tested a single injection of SHR-3045 in 16 healthy adults to see if it is safe and how the body processes it. The drug is being developed as a potential treatment for rheumatoid arthritis, an autoimmune disease that causes joint pain and swelling. Because this…

This study looked at how safe and effective peficitinib is for people with rheumatoid arthritis (RA) in everyday medical practice. About 3,000 patients who were starting peficitinib for the first time took part. Researchers tracked side effects and measured disease activity using…

This study looked at how safe and effective upadacitinib is for Korean patients with rheumatoid arthritis, atopic dermatitis, ankylosing spondylitis, or psoriatic arthritis. Over 2,300 adults took the drug as prescribed by their doctor and were followed for about 28 weeks. Resear…

This early-stage trial tested ARD-885, a new oral drug that targets two proteins involved in inflammation, in 94 healthy volunteers and people with rheumatoid arthritis. The main goal was to check safety and how the body processes the drug. Researchers gave single and multiple do…

This completed study followed 413 Canadian adults with moderate to severe rheumatoid arthritis who were prescribed upadacitinib by their doctors. Researchers tracked how well the drug controlled symptoms like joint pain and stiffness over 24 months. The goal was to see if the dru…

This study looked at whether the drug Acthar can reduce inflammation and improve symptoms during a rheumatoid arthritis (RA) flare. Forty adults with RA who were having a flare took part. Researchers used ultrasound and disease activity scores to measure changes after treatment.

This study tests whether learning Argentine tango can increase overall physical activity in people with chronic inflammatory arthritis, such as rheumatoid arthritis or spondyloarthritis. Participants will take tango sessions that focus on body awareness, movement, and connection …

This trial tests whether optimizing protein intake—through dietary counseling and whey protein supplements—can reduce household work limitations and overall disability in women with rheumatoid arthritis. Participants will aim for 1.0 gram of protein per kilogram of body weight da…

This pilot study tested whether a care model called PREVAIL is practical and acceptable for adults with rheumatoid arthritis. The model includes a screening tool to identify activity limitations, a recommendation to the rheumatologist for exercise or physical therapy, and an onli…

This study tested whether a device that gently stimulates the vagus nerve through the ear could help control rheumatoid arthritis in one patient who had their spleen removed. The patient used the device at home for 24 months and visited the clinic every two months for checkups. T…

This study tested whether applying cold to painful joints can reduce pain and improve quality of life in people with rheumatoid arthritis. 90 patients with active pain participated. The goal was to see if this simple, low-cost method could be a helpful addition to standard care.

This study tested whether Siwan sand therapy (warm sand baths followed by olive oil massage) could improve lung function, pain, and daily activity in people with rheumatoid arthritis. Thirty adults with moderate to severe RA were split into two groups: one received sand therapy f…

This study tests whether a smartphone-based digital assessment can measure rheumatoid arthritis activity as well as a standard doctor-performed exam. Adults with rheumatoid arthritis will complete a digital questionnaire, record guided videos of their joint movements, and then ha…

This study looks at whether a blood test called Vectra can help doctors make better treatment choices for people with rheumatoid arthritis (RA). The test gives a score from 1 to 100 to show how active the disease is. About 1500 adults with RA will be split into two groups: one wh…

This study is looking at how nutrition affects disease activity in people with rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will measure the nutritional status of 460 participants using several different tools and compare it to how act…

This study tested whether a new version of the arthritis drug abatacept (called KSHB002) works similarly to the approved drug Orencia. Three hundred healthy adults received a single injection of either the new drug or Orencia. Researchers measured drug levels in the blood, checke…

This study looked at the safety of the drug RINVOQ in over 4,200 Japanese adults with rheumatoid arthritis, a condition causing joint pain and swelling. Researchers reviewed medical records for three years to count serious infections and other side effects that happened during no…

This completed study looked at nearly 7,000 adults with inflammatory joint diseases like rheumatoid arthritis and psoriatic arthritis. Researchers compared two versions of a standard health survey (EQ-5D-3L and EQ-5D-5L) to see which one better measures health and quality of life…

This completed study looked at whether adding an integrated care model—including traditional Chinese medicine—to standard treatment could lower inflammation and depressive symptoms in people with rheumatoid arthritis. Researchers measured blood markers of inflammation and used a …

This study followed 82 postmenopausal women with rheumatoid arthritis to see how their bone density changed over time. Researchers compared different arthritis medications and osteoporosis treatments to understand which approaches best protect bone health. The goal was to gather …

This completed study looked at the safety of the arthritis drug abatacept in over 38,000 people with rheumatoid or psoriatic arthritis in Denmark. Researchers used a national health registry to track rates of cancers and other side effects. The goal was to better understand the d…

This study looked at how much patients with rheumatoid arthritis or knee osteoarthritis know about cardiovascular disease risks. Researchers surveyed 120 adults aged 40 and older using a 28-item knowledge scale. The goal was to compare awareness between the two groups and identif…