RHEUMATIC DISEASES

This study tests a new medicine called SPY002-072 in adults with moderate-to-severe rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis. About 285 participants will receive either the drug or a placebo to see if it reduces joint swelling and pain. The goal is to…

This study tests a new treatment using specially engineered immune cells (CAR-NK cells) in children aged 5 and older with severe rheumatic diseases like lupus that have not responded to standard therapies. The cells are designed to target and destroy faulty immune cells that caus…

This study is testing a new blood test that may help doctors choose the most effective drug for each person with rheumatic diseases like rheumatoid arthritis or lupus. The test looks at how a person's immune cells react to different medications before treatment starts. The goal i…

This study is building a large database and sample bank from 5,000 adults with various rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will use this information to find links between patient outcomes and biological markers. The goal is to…

This study involves 70 children and young people (ages 0-18) with rheumatic conditions who have taken steroids in the last two years. Researchers will hold focus groups and interviews to understand how steroids affect their daily life and well-being. The goal is to develop a pati…

This study aims to learn more about the causes of rheumatic diseases, such as arthritis, and why they often affect minority groups more severely. Researchers will observe up to 7,500 adults with known or suspected rheumatic disease, providing standard medical care and tests. No e…

This study looks at whether a special tool for doctors and easy-to-read brochures for patients can help reduce the use of potentially harmful medications in adults aged 60 and older with rheumatic conditions like arthritis or lupus. Researchers will follow 100 participants for ab…