RESPIRATORY TRACT DISEASES
Clinical trials for RESPIRATORY TRACT DISEASES explained in plain language.
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Can a tiny adjustment to a mouthpiece make a big difference for sleep apnea?
Disease control CompletedThis study tested how small adjustments to a dental mouthpiece affect sleep apnea. Researchers worked with 20 adults who have moderate sleep apnea or severe apnea where a CPAP machine didn't work. They measured sleep breathing and daytime sleepiness as they moved the mouthpiece f…
Matched conditions: RESPIRATORY TRACT DISEASES
Sponsor: Centre Hospitalier de Valence • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug fights common cold to protect vulnerable lungs
Disease control CompletedThis study tested an experimental drug called vapendavir to see if it could reduce serious lung symptoms in people with COPD after they caught a common cold virus. Researchers gave the drug or a placebo to 52 adults with moderate COPD who were then exposed to the virus. The main …
Matched conditions: RESPIRATORY TRACT DISEASES
Phase: PHASE2 • Sponsor: Altesa Biosciences, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Simple vitamin pill could cut lung crises in half for sickle cell kids
Disease control CompletedThis study tested whether taking a daily vitamin D pill could reduce serious lung problems in children and teens with sickle cell disease. Researchers compared daily vitamin D to a larger monthly dose over two years to see which was better at preventing infections, asthma attacks…
Matched conditions: RESPIRATORY TRACT DISEASES
Phase: PHASE2 • Sponsor: Columbia University • Aim: Disease control
Last updated Mar 10, 2026 12:54 UTC
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Study aims to spare cancer patients unnecessary radiation scans for blood clots
Diagnosis CompletedThis study tested if a step-by-step checklist (the YEARS algorithm) could safely rule out dangerous blood clots in the lungs of cancer patients without always needing a CT scan. It compared this method to the standard approach of doing a CT scan for everyone. The goal was to see …
Matched conditions: RESPIRATORY TRACT DISEASES
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC
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IV Mucus-Busters show promise for easier breathing
Symptom relief CompletedThis study tested if two intravenous (IV) drugs could help adults with lung diseases like bronchitis who have trouble coughing up thick mucus. About 333 hospitalized patients in China received either N-acetylcysteine (NAC), ambroxol, or a placebo for one week. The main goal was t…
Matched conditions: RESPIRATORY TRACT DISEASES
Phase: PHASE3 • Sponsor: Zambon SpA • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC
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Scientists search for clues in mysterious lung disease
Knowledge-focused CompletedThis study aimed to better describe a lung condition called idiopathic bronchiectasis, where the airways become abnormally stretched and widened for unknown reasons. Researchers observed 275 adults who had this unexplained lung damage to document their physical traits, lung image…
Matched conditions: RESPIRATORY TRACT DISEASES
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:05 UTC