RESPIRATORY TRACT DISEASES

This study tested whether a booster vaccine for a bird flu strain (H5N6) is safe and boosts immunity in adults. About 260 people who had either a prior H5N1 vaccine or a placebo took part. Researchers measured antibody levels after one or two booster shots to see how well the bod…

This study tested an experimental drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if the drug could reduce severe cold symptoms caused by rhinovirus, a common cold virus. Participants were given either vapendavir or a placebo and monito…

This study looked at whether taking vitamin D every day can lower the risk of serious lung problems in children and teens with sickle cell disease. Lung issues like infections and acute chest syndrome are major causes of illness in this group. The study involved 58 participants a…

This study looked at whether a simple checklist called the YEARS algorithm can safely rule out dangerous blood clots in the lungs (pulmonary embolism) in people with active cancer, without needing a CT scan. About 700 participants were randomly assigned to either the YEARS approa…

This study tested whether a one-week course of intravenous N-acetylcysteine (NAC) helps adults with respiratory diseases cough up thick mucus more easily. 333 hospitalized patients in China received either NAC, an active comparator (ambroxol), or a placebo. Results showed NAC was…

This study looked at how much each millimeter of advancement of an oral appliance helps people with sleep apnea. Twenty adults with moderate or severe sleep apnea (who couldn't use CPAP) took part. The goal was to see how the device's position affects breathing pauses and tiredne…

This study looked at 275 adults with a lung condition called bronchiectasis, where airways are stretched and trap mucus, leading to infections. The goal was to better describe the physical traits, lung scans, and germs in the lungs of people with no known cause. Participants gave…