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This study looked at how the drug selpercatinib is handled by the body in people with kidney problems compared to healthy people. 37 adults took a single dose of the drug, and researchers measured how much got into the blood and how quickly it was removed. The goal was to gather …

This study looked at how the antibiotic ceftriaxone moves through the blood and belly fluid in 20 people with severe liver cirrhosis and fluid buildup (ascites), some of whom also had kidney problems. Researchers collected leftover blood and fluid samples during routine care to m…

This study looked at how the drug LY3537982 moves through the body in people with different levels of kidney function. Researchers compared 32 participants with normal kidneys to those with moderate or severe kidney problems. The goal was to find the right dose for people with ki…

This study looked at how well pre-mixed solutions work for critically ill patients who need continuous kidney dialysis. Researchers collected data from 228 patients in China to see how long filters lasted and how the body responded. The goal was to understand if these ready-to-us…

This early-stage study tested the safety and tolerability of a new drug called KBP-5074 in 26 adults, including healthy volunteers and people with mild to moderate kidney impairment. Researchers measured how the drug moves through the body and checked for side effects. The goal w…

This study looked at 120 people having hand or wrist surgery to see if kidney failure or diabetes changes how long a nerve block lasts. Researchers measured the time it took for feeling to return after the block. The goal was to understand how these metabolic conditions affect re…

This study tested a new method (SFATI) for measuring blood pressure in 90 people with severe kidney failure. The goal was to see if it works as well as the standard arm-cuff method, especially when arteries are stiff or calcified. The study is complete and aims to improve blood p…

This study looked at how the drug BI 1015550 is absorbed in people with and without kidney problems. 26 adults took a single tablet, and researchers measured drug levels in their blood over two weeks. The goal was to see if kidney issues change how the drug behaves, which helps d…

This study looked at 5 adults with Fabry disease who have been on enzyme replacement therapy since childhood for about 15 years. Researchers measured kidney function and heart health to see how well the long-term treatment worked. The goal was to gather follow-up data, not to tes…

This study looked at how different levels of kidney function affect the way the body processes iclepertin, a medicine being developed for brain diseases. 36 adults with and without kidney problems took a single tablet of iclepertin. Researchers measured the drug levels in their b…