REM SLEEP BEHAVIOR DISORDER
Clinical trials for REM SLEEP BEHAVIOR DISORDER explained in plain language.
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Could a new pill calm brain inflammation and slow Parkinson's-Linked sleep disorder?
Disease control OngoingThis study tests whether an oral drug called PXS-4728A can reduce brain inflammation in 40 adults aged 50-80 with isolated REM sleep behavior disorder (iRBD), a condition often leading to Parkinson's disease. Participants receive either the drug or a placebo for 12 weeks, and bra…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: Syntara • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Blood pressure drug shows promise in slowing Parkinson's progression
Disease control OngoingThis study looks at whether terazosin, a drug usually used for high blood pressure, can slow the progression of Parkinson's disease. Researchers are tracking changes in heart and brain scans of 15 people who are either in early stages or at high risk for Parkinson's. The goal is …
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Could a common heart pill slow Parkinson's? small trial aims to find out
Disease control OngoingThis phase 2 trial tests whether carvedilol, a drug usually used for heart conditions, can slow the loss of dopamine transporters in the brain and delay Parkinson's symptoms. It follows 15 people with REM sleep behavior disorder and other early Parkinson's risk factors over three…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Brain scan study aims to sharpen diagnosis of Parkinson's and dementia
Diagnosis ENROLLING_BY_INVITATIONThis study uses a special brain scan called DaTscan to look at how certain brain diseases affect the brain. Researchers will scan 500 adults with conditions like Parkinson's disease, dementia, mild cognitive impairment, or REM sleep behavior disorder. The goal is to see if DaTsca…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Lifestyle trio tested as Parkinson's symptom soother
Symptom relief OngoingThis study is testing whether a 6-month program of online exercise classes, guided meditation, and nutrition advice can improve thinking, sleep, and overall health in people with Parkinson's disease. 60 participants aged 40 to 85 will take part, with some starting the program rig…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: University of British Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Sleep disorder study could pave way for Parkinson's prevention
Knowledge-focused ENROLLING_BY_INVITATIONThis study enrolls 500 adults with a sleep condition called REM sleep behavior disorder (RBD), which often leads to Parkinson's disease or related brain disorders. Researchers will track symptoms like thinking, movement, and smell to develop a rating scale. The goal is to prepare…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Could a common heart pill delay Parkinson's? small study hints at possibility
Knowledge-focused OngoingThis study looks at whether carvedilol, a drug used for heart failure, can reverse early heart changes seen in people with a sleep disorder that puts them at high risk for Parkinson's disease. Fifteen participants with REM sleep behavior disorder or reduced sense of smell will ta…
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: Michele Tagliati, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can a common drug reveal Parkinson's before symptoms start?
Knowledge-focused OngoingThis study looks at whether terazosin, a drug used for high blood pressure, can change heart nerve activity in people at high risk for Parkinson's disease. Researchers are studying 15 adults with REM sleep behavior disorder (a strong early sign of Parkinson's) to see if the drug …
Matched conditions: REM SLEEP BEHAVIOR DISORDER
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC