RECURRENT PLASMA CELL MYELOMA

This study is testing a two-part treatment plan for adults with multiple myeloma that has come back or stopped responding to other therapies. It combines an immunotherapy drug with two different chemotherapy drugs to try to control the cancer for longer. The main goal is to see h…

This study is testing whether the immunotherapy drug nivolumab can help control blood cancers that have returned, stopped responding, or are still detectable after a patient has already received CAR-T cell therapy. It is for adults with specific types of lymphoma, leukemia, or mu…

This early-stage trial is testing whether a patient's own immune cells can be grown in a lab to fight multiple myeloma that has returned or stopped responding to other treatments. Doctors take T-cells from the patient's blood, grow them to target a specific protein found on cance…

This early-stage trial is testing the safety of combining two drugs—venetoclax and tocilizumab—for multiple myeloma that has returned or stopped responding to treatment. The study focuses on patients whose cancer has a specific genetic change called t(11;14). Researchers want to …

This study is testing a modified stem cell transplant procedure for patients with high-risk blood cancers. The goal is to see if using specific chemotherapy drugs in a timed sequence before and after the transplant can better control the cancer while reducing harmful immune react…

This early-phase trial is testing the safety and best dose of a two-drug combination (selinexor and choline salicylate) for adults with advanced blood cancers that have returned or stopped responding to standard treatments. The study includes patients with non-Hodgkin lymphoma, H…

This study is testing whether adding a modified virus (pelareorep) to a combination of standard chemotherapy and immunotherapy drugs is safe and more effective for people with multiple myeloma that has come back or stopped responding to treatment. The goal is to see if the virus …

This study is testing a combination of three drugs—isatuximab, carfilzomib, and pomalidomide—for adults with multiple myeloma that has come back (relapsed) or stopped responding to treatment (refractory). The goal is to see if this combination can control the cancer and for how l…

This study aims to understand how often advanced cancer patients experience severe weight loss and loss of appetite, a condition called cachexia. Researchers are also measuring the emotional and psychological stress this causes for both the patients and their primary family careg…