Can a cold virus help fight myeloma? new combo trial launches

This early-stage study tests whether adding a lab-modified reovirus (pelareorep) to a standard drug combination (bortezomib, dexamethasone, and pembrolizumab) can safely improve outcomes for people with multiple myeloma that has relapsed or become resistant. About 10 participants who have already tried at least three prior treatments will receive the therapy. The main goals are to check safety and see how many patients respond, but this is not a cure — it aims to control the disease.