Immune cells trained to hunt MUC1 protein show promise in hard-to-treat myeloma

NCT ID NCT05411497

First seen Nov 04, 2025 · Last updated Apr 29, 2026 · Updated 25 times

Summary

This early-phase trial tests a personalized therapy where a patient's own T-cells are trained to recognize and attack the MUC1 protein on myeloma cells. The study enrolls 5 adults with multiple myeloma that has returned or stopped responding to at least three prior treatments. The main goal is to check safety and find the best dose, while also watching for any tumor shrinkage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RECURRENT PLASMA CELL MYELOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

Conditions

Explore the condition pages connected to this study.