RECURRENT GLIOMA
Clinical trials for RECURRENT GLIOMA explained in plain language.
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New hope for kids with tough cancers: drug targets unique genetic flaw
Disease control OngoingThis study is testing a drug called larotrectinib in children and young adults (ages 1-21) whose advanced solid tumors, lymphomas, or histiocytic disorders have returned or not responded to standard treatments. The drug is given to patients whose tumors have a specific genetic ch…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for Tough-to-Treat cancers: drug trial targets specific genetic flaw
Disease control OngoingThis study is testing whether the drug olaparib can help control advanced cancers that have a specific genetic change (IDH1 or IDH2 mutation) and have stopped responding to standard treatments. It is enrolling adults with certain brain tumors, bile duct cancer, or other solid tum…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Targeted drug trial offers hope for kids with Tough-to-Treat cancers
Disease control OngoingThis study is testing an oral drug called ulixertinib in children and adolescents whose advanced cancers have not responded to standard treatments and have a specific genetic change in a cell pathway called MAPK. The main goal is to see if the drug can shrink tumors and control t…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Cancer trial matches drugs to your Tumor's DNA
Disease control OngoingThis large national trial is testing whether choosing cancer drugs based on the specific genetic changes found in a patient's tumor is more effective than standard approaches. It is for adults with advanced solid tumors, lymphoma, or multiple myeloma that have progressed after at…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New hope for kids with tough cancers: treatment guided by tumor genetics
Disease control OngoingThis study is testing a personalized approach for children and young adults with advanced cancers that have come back or stopped responding to standard treatments. Doctors first test the genetic makeup of a patient's tumor to look for specific changes. If a matching change is fou…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Engineered immune cells injected into brain to fight aggressive cancer
Disease control OngoingThis early-phase study is testing the safety and best dose of a personalized immune cell therapy for adults with recurrent or treatment-resistant malignant brain tumors (glioma). Doctors collect a patient's own immune cells, genetically modify them in a lab to recognize and attac…
Matched conditions: RECURRENT GLIOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New brain scan could reveal hidden tumor secrets
Diagnosis OngoingThis study is testing a new, experimental type of MRI scan designed to see brain tumors (gliomas) in more detail. The goal is to see if this scan can provide better information about the tumor's biology and how it might respond to treatment. The study involves people with brain t…
Matched conditions: RECURRENT GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Diagnosis
Last updated Apr 01, 2026 14:41 UTC
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Scientists probe experimental Drug's path into brain tumors
Knowledge-focused OngoingThis early study aims to understand if an experimental drug called niraparib reaches brain tumor tissue effectively. It involves 16 adults with recurrent, slow-growing brain tumors (gliomas) who are already scheduled for surgery. Researchers will measure how much of the drug gets…
Matched conditions: RECURRENT GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC