New study measures drug levels in brain tumors before surgery

NCT ID NCT05406700

First seen Sep 30, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This early-phase trial enrolls 16 adults with recurrent IDH-mutant gliomas who are scheduled for surgery. Participants take niraparib for one month before their operation so researchers can measure how much drug gets into the tumor and how it affects cancer cells. The goal is to gather information, not to treat the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.