RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Clinical trials for RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4 explained in plain language.
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Experimental drug triapine paired with radiation targets recurrent brain cancers
Disease control Recruiting nowThis early-phase trial tests the safety and best dose of the drug triapine when given together with radiation therapy for people whose glioblastoma or astrocytoma has come back. Triapine works by blocking enzymes that cancer cells need to grow, while radiation kills cancer cells …
Matched conditions: RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Gene-Edited immune cells take on aggressive brain tumors
Disease control Recruiting nowThis phase 1 trial tests a new type of immunotherapy for people with recurrent or progressive high-grade gliomas, including glioblastoma. The treatment uses the patient's own T cells, which are genetically modified in the lab to target a protein called IL13Rα2 found on tumor cell…
Matched conditions: RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Engineered immune cells target deadly brain tumors in new trial
Disease control Recruiting nowThis early-phase trial tests the safety of a new treatment for people with recurrent or progressive high-grade glioma, a serious brain cancer. The therapy uses the patient's own immune cells, modified in a lab to recognize and attack tumor cells, and delivers them directly into t…
Matched conditions: RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Experimental drug aims to boost immune attack on aggressive brain tumors
Disease control Recruiting nowThis phase 2 trial tests a new drug called GI-102, alone or with the immunotherapy pembrolizumab, given before surgery to people with recurrent or progressive glioblastoma (a fast-growing brain cancer). The goal is to see if these drugs can increase cancer-fighting immune cells i…
Matched conditions: RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Fat-Derived stem cells injected into brain during surgery to fight glioblastoma
Disease control Recruiting nowThis early-stage trial tests whether stem cells taken from fat tissue can be safely injected into the brain during surgery for recurrent glioblastoma. The stem cells are meant to attack remaining tumor cells and make them more sensitive to chemotherapy. About 20 adults whose brai…
Matched conditions: RECURRENT ASTROCYTOMA, IDH-MUTANT, GRADE 4
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC