Fat-Derived stem cells injected into brain during surgery to fight glioblastoma
NCT ID NCT05789394
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether stem cells taken from fat tissue can be safely injected into the brain during surgery for recurrent glioblastoma. The stem cells are meant to attack remaining tumor cells and make them more sensitive to chemotherapy. About 20 adults whose brain cancer has returned will receive the treatment, and researchers will look for side effects and the best dose to use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
allogeneic adipose-derived mesenchymal stem cells (AMSCs)
What this could lead to
If it works, this could point toward a new way to slow or stop recurrent glioblastoma by delivering stem cells directly into the brain during surgery.
What could go wrong
This is a very early Phase 1 trial with only 20 people, focused on safety and dosing. It may not show any benefit, and there are risks from the surgery and the stem cell injection itself.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224-9980, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••