RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Clinical trials for RECURRENT ADULT ACUTE MYELOID LEUKEMIA explained in plain language.
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Precision radiation may boost stem cell transplant success in tough leukemias
Disease control OngoingThis study tests a precise radiation method called total marrow and lymphoid irradiation (TMLI) given with two chemotherapy drugs (etoposide and cyclophosphamide) before a donor stem cell transplant. The goal is to safely deliver higher radiation doses to the bone marrow to wipe …
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jul 02, 2026 06:00 UTC
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New cocktail of cancer drugs tested for tough leukemia
Disease control OngoingThis early-phase trial tests a combination of three drugs — bortezomib, sorafenib, and decitabine — in patients with acute myeloid leukemia (AML), especially those who are older or have hard-to-treat forms. The main goal is to find the safest dose and see how well patients tolera…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New drug combo shows promise for MDS and AML
Disease control OngoingThis study tests two drugs, vorinostat and azacitidine, together in people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The goal is to find the best dose and see if the combination is safe and effective. About 135 participants will take part in this early-…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Precision radiation may boost second stem cell transplants for relapsed blood cancers
Disease control TerminatedThis early-stage trial tests a precise type of radiation (IMTMI) given with chemotherapy before a second donor stem cell transplant for people with advanced blood cancers that have returned. The goal is to find the safest dose and see if it can reduce side effects and prevent the…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New strategy aims to tame common virus after stem cell transplants
Disease control OngoingThis study tests a modified plan to prevent and treat cytomegalovirus (CMV) infection in people with blood cancers who have had a donor stem cell transplant. CMV is a common virus that can cause serious problems after transplant. The study involves 153 participants and looks at w…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New drug combo aims to tame AML in patients too frail for strong chemo
Disease control OngoingThis phase 1 trial tests the combination of nintedanib and azacitidine in older adults with acute myeloid leukemia (AML) who are not candidates for intensive chemotherapy. The goal is to find the safest dose of nintedanib when given with azacitidine and to see how well patients t…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Engineered immune cells take aim at stubborn blood cancers
Disease control OngoingThis early-phase trial tests a new type of immunotherapy for patients with acute myeloid leukemia (AML) or blastic plasmacytoid dendritic cell neoplasm (BPDCN) that has returned or not responded to treatment. Researchers take a patient's own (or a donor's) T-cells, modify them in…
Matched conditions: RECURRENT ADULT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 26, 2026 17:52 UTC