PULMONARY NODULES

This trial tests a new method called Longitude-Latitude-Depth (LLD) localization, which uses 3D mapping from a CT scan to guide surgeons to small lung nodules without a needle puncture. It is being compared to the standard CT-guided needle localization in adults with single perip…

This study will test whether a robot-assisted bronchoscope can safely take a tissue sample (biopsy) and then immediately destroy a suspicious lung nodule using heat (radiofrequency ablation) in a single procedure. About 76 adults with small, early-stage lung nodules who cannot or…

This trial tests whether a robot can help doctors more accurately target and destroy small lung nodules (ground-glass opacities) using microwave heat, compared to the standard CT-guided method. About 116 adults with early-stage lung cancer who cannot have surgery will be randomly…

This study compares a new robot-assisted system to the standard manual method for taking a tissue sample (biopsy) from a lung nodule. The goal is to see if the robot is as safe and effective at diagnosing lung cancer or other conditions. About 158 adults with suspicious lung nodu…

This study compares a 'tubeless' approach to standard care for people having minimally invasive surgery to remove small lung nodules. The tubeless group gets a laryngeal mask instead of a breathing tube and no chest drain after surgery. The goal is to see if they recover better w…

This study compares a newer anesthesia method where patients breathe on their own during lung surgery to the standard method using a breathing tube and machine. About 1,600 people having minimally invasive lung nodule removal will be randomly assigned to one of the two methods. T…

This study tests whether a home exercise program delivered through a smartphone app can improve hand strength, muscle endurance, and emotional well-being in 60 adults scheduled for lung nodule surgery. Participants will do aerobic, resistance, and breathing exercises for at least…

This study will develop an artificial intelligence model that uses a patient's series of CT scans over time to predict whether a lung nodule will grow or become cancerous. Researchers will analyze scans from nearly 5,000 people to train the AI to recognize different growth patter…

This study compares a new electromagnetic navigation system to standard CT scans for guiding surgeons to small lung nodules during surgery. About 400 adults with nodules up to 2 cm will be randomly assigned to one method. The goal is to see which approach helps surgeons find and …