PROGRESSIVE PULMONARY FIBROSIS

This study tests an inhaled form of pirfenidone (AP01) in 375 adults with progressive pulmonary fibrosis (PPF), a condition where lung scarring worsens over time. Participants receive either a high dose, low dose, or placebo twice daily for 52 weeks, alongside their usual care. T…

This study tests whether taking quercetin, a natural compound found in foods like apples and onions, can slow lung scarring and improve breathing in people with pulmonary fibrosis. About 100 adults with this chronic lung disease will either receive quercetin pills plus their usua…

This phase 3 study tests whether an inhaled medication called treprostinil can slow the worsening of lung function in people with progressive pulmonary fibrosis (PPF), a condition where lung scarring gets worse over time. About 698 adults with PPF will receive either the drug or …

This study looks at the long-term safety of a daily pill called nerandomilast for people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). Participants must have completed a previous study with the same drug. The goal is to see if the drug is safe …

This study looks at the long-term safety of an inhaled medication for people with progressive lung scarring (pulmonary fibrosis). Participants must have completed a prior Avalyn Pharma study of the same drug. Researchers will monitor side effects and lung function over time to se…

This study tests a new way to organize follow-up care for people with interstitial lung disease (ILD). Instead of making several separate trips for tests, lab work, and doctor visits, the new approach bundles everything into one coordinated hospital visit. The goal is to reduce t…

This study is testing a mobile app called SUPPORT-T that helps people with progressive pulmonary fibrosis (a type of lung scarring) and their caregivers get palliative care support at home. The app includes a 9-week guided program and virtual support groups over a year. Researche…

This study looks at how anti-fibrotic medications affect body composition in people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). Researchers will use simple, non-invasive tools like bioelectrical impedance analysis (BIA) and muscle ultrasound …

This study follows 500 adults with progressive pulmonary fibrosis (a type of lung scarring) for 24 months. Researchers will collect medical data, images, and samples to better understand the disease and improve how it is classified and predicted. No new treatments are tested; the…