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500-Patient study aims to unlock secrets of progressive lung scarring

NCT ID NCT06855329

Recruiting now Knowledge-focused Sponsor: University of Massachusetts, Worcester Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 500 adults with progressive pulmonary fibrosis (a type of lung scarring) for 24 months. Researchers will collect medical images, lung function tests, and blood samples to better classify the disease and predict its course. The goal is to improve how doctors identify and manage this condition, not to test a new drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to better ways to identify and predict progressive pulmonary fibrosis, helping doctors tailor treatments earlier.
What could go wrong
This is an observational study, not testing a treatment, so it won't directly change patient care. Results may take years to influence practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fibrotic hypersensitivity pneumonitis idiopathic interstitial pneumonia interstitial lung disease pulmonary fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTERSTITIAL LUNG DISEASE PROGRESSIVE PULMONARY FIBROSIS

Contacts and locations

Locations

  • Austin Health

    NOT_YET_RECRUITING

    Melbourne, Victoria, 3000, Australia

  • Prince Charles Hospital

    NOT_YET_RECRUITING

    Brisbane, Queensland, 4032, Australia

  • Royal Brompton

    NOT_YET_RECRUITING

    London, Greater London, SW3 6NP, United Kingdom

  • Royal Prince Alfred Hospital

    NOT_YET_RECRUITING

    Camperdown, New South Wales, 2050, Australia

  • University College Dublin

    NOT_YET_RECRUITING

    Dublin, Ireland, D04 T6F4, Ireland

  • University Hospital Southampton

    NOT_YET_RECRUITING

    Southampton, Hampshire, SO16 7DL, United Kingdom

    Contact Email: •••••@•••••

  • University of British Columbia

    NOT_YET_RECRUITING

    Vancouver, British Columbia, V6Z 1Y6, Canada

  • University of Calgary

    NOT_YET_RECRUITING

    Calgary, Alberta, T2N 4Z6, Canada

  • University of Massachusetts Chan Medical School

    RECRUITING

    Worcester, Massachusetts, 01655, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Texas Southwestern

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

  • University of Virginia

    NOT_YET_RECRUITING

    Charlottesville, Virginia, 22908, United States

  • University of Washington

    NOT_YET_RECRUITING

    Seattle, Washington, 98195, United States

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