PROBIOTIC INTERVENTION

This study tests whether a probiotic (Lactobacillus paracasei) or the drug semaglutide can help overweight or obese adults lose weight and improve metabolism. Over 12 weeks, 140 participants will follow a reduced-calorie diet and lifestyle program while taking one of these or a p…

This study is testing whether adding probiotics to standard pulmonary rehabilitation can help control inflammation and improve breathing, physical function, and nutrition in people with COPD. Researchers will measure markers like interleukin-6 and track exercise capacity. The goa…

This study tests whether adding a probiotic (Lactobacillus crispatus) to the antidepressant sertraline helps reduce depression symptoms more than sertraline alone in teens aged 12-18 with major depressive disorder. Sixty participants will take either the probiotic or a placebo fo…

This study tests whether adding multi-strain probiotics to the antidepressant sertraline helps teenagers aged 12-18 with major depression feel better than sertraline alone. Over 8 weeks, 120 participants will take either the combination or sertraline with a placebo. Researchers w…

This pilot study is testing a multi-strain liquid probiotic in 20 adults who report having constipation. Participants take 70 ml of the probiotic daily for 28-35 days. The goal is to see if it improves constipation symptoms and quality of life, offering a possible alternative for…

This pilot study tests whether taking a commercial probiotic daily for 4 weeks can increase blood levels of folate, vitamin B12, and vitamin B6 in healthy women aged 18–40. Participants will take either one or two capsules per day and provide blood and stool samples. The goal is …