PRADER-WILLI SYNDROME
Clinical trials for PRADER-WILLI SYNDROME explained in plain language.
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New program aims to help Prader-Willi patients keep weight off
Disease control CompletedThis study tested a 5-week hospital program combining physical activity, nutrition advice, and education for 128 adults with Prader-Willi syndrome. The goal was to help patients stabilize or lose weight 6 months after leaving the hospital. The program focuses on changing daily ha…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Growth hormone shows promise for Prader-Willi syndrome in japanese trial
Disease control CompletedThis study tested a growth hormone called somatropin in 33 Japanese people with Prader-Willi syndrome, a genetic condition that causes weak muscles, obesity, and developmental delays. The goal was to see if the drug improves body composition by increasing lean muscle mass and red…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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New hope for daytime drowsiness in Prader-Willi syndrome
Symptom relief CompletedThis study tested a drug called pitolisant to see if it could safely reduce severe daytime sleepiness in people with Prader-Willi syndrome, a genetic condition. 65 participants aged 6 to 65 took either the drug or a placebo for 11 weeks. The main goal was to measure changes in sl…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Symptom relief
Last updated Jun 17, 2026 12:06 UTC
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Can a 'love hormone' spray ease behavior issues in Prader-Willi syndrome?
Symptom relief CompletedThis study tested whether oxytocin nasal spray can improve behavior and social skills in adults with Prader-Willi syndrome, a genetic condition that causes behavioral and eating problems. Fifty adults with confirmed Prader-Willi syndrome took part. Researchers measured changes in…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 17, 2026 12:04 UTC
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Hormone clues may explain why babies with rare disorder suddenly gain weight
Knowledge-focused CompletedThis study followed 215 infants with Prader-Willi syndrome to track how hormones that control appetite and feeding change during the first four years of life. The goal was to understand why these children go from poor feeding as babies to severe overeating and obesity later. Rese…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:08 UTC