PLASMA CELL MYELOMA

This study tested whether giving a standard multiple myeloma drug at home is a practical option for patients. Twenty adults already receiving the drug Darzalex Faspro received some of their injections at home instead of at the cancer center. The main goal was to see if home treat…

This study was the first time a new drug called SAR442085 was tested in people. It aimed to find a safe dose and see if it could help control multiple myeloma in patients whose cancer had returned or stopped responding to many standard treatments. The trial involved a small group…

This study tested whether adding a new drug called isatuximab to a standard two-drug therapy could better control multiple myeloma that had returned or stopped responding to prior treatments. It involved 302 adults whose cancer had progressed after 1 to 3 previous lines of therap…

This study tested if adding two more drugs (ixazomib and dexamethasone) to a standard maintenance drug (lenalidomide) was better at controlling residual multiple myeloma after a stem cell transplant. It involved 42 patients who still had small amounts of cancer detectable after t…

This study tested whether patients with multiple myeloma or non-Hodgkin lymphoma could recover just as quickly after a stem cell transplant without receiving a standard recovery-boosting drug (G-CSF). The main goal was to see if skipping this drug led to a similar time until pati…

This study tested whether adding the drug daratumumab before and after a stem cell transplant could help patients with multiple myeloma achieve deeper remission. The trial involved 49 patients eligible for transplant and measured whether cancer cells became undetectable after tre…

This study tested a two-drug maintenance therapy given after a patient's own stem cell transplant to help prevent multiple myeloma from coming back. Thirty patients received alternating cycles of two oral medications (ixazomib and lenalidomide) for up to two years. The main goal …

This study tested a two-step, lower-intensity stem cell transplant for patients with high-risk blood cancers like leukemia and lymphoma. The goal was to use milder chemotherapy and radiation before the transplant to reduce side effects while still allowing the donor's immune cell…

This study compared two tools used to take bone marrow samples from patients with blood cancers like multiple myeloma. Researchers tested whether a new battery-powered drill system was better than the traditional manual needle in terms of the quality of the sample collected, how …

This study aimed to see if a special health assessment for older adults could help predict who might experience more side effects from chemotherapy for multiple myeloma. Researchers followed 56 patients aged 65 and older, using questionnaires, tests, and blood samples to measure …