PARKINSONS DISEASE
Clinical trials for PARKINSONS DISEASE explained in plain language.
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New drug targets Parkinson's protein in first human test
Disease control Recruiting nowThis study tests an experimental drug called ALN-SNCA in 46 people with early Parkinson's disease. The drug is designed to lower levels of a harmful protein, alpha-synuclein, in the brain. The main goal is to check if the drug is safe and tolerable, and to see how it moves throug…
Matched conditions: PARKINSONS DISEASE
Phase: PHASE1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Could a leg nerve graft help the brain? new trial for Parkinson's and MSA
Disease control Recruiting nowThis early-stage study tests if implanting a small piece of the participant's own leg nerve into a key brain area is safe and feasible for people with early Parkinson's disease or Multiple System Atrophy. Seven people will take part; four will get the nerve graft and three will h…
Matched conditions: PARKINSONS DISEASE
Phase: PHASE1 • Sponsor: Craig van Horne, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New registry to monitor brain ultrasound for Parkinson's tremors
Disease control Recruiting nowThis study tracks people with advanced Parkinson's disease who receive a treatment called Exablate, which uses focused ultrasound to target a small area in the brain. The goal is to see how well it reduces medication-resistant motor problems like shaking and stiffness. Researcher…
Matched conditions: PARKINSONS DISEASE
Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Ultrasound opens brain barrier to deliver Parkinson's drug in first human test
Disease control Recruiting nowThis early-phase trial tests whether a focused ultrasound device can safely open the blood-brain barrier to deliver a missing enzyme (GCase) directly into the brains of 14 people with Parkinson's disease. The goal is to see if this delivery method is safe and feasible, not yet to…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Gentle touch may ease sleepless nights for Parkinson's patients
Symptom relief Recruiting nowThis study tests whether osteopathic manipulative treatment (OMT) — a hands-on therapy using gentle techniques on the head, neck, and ribs — can improve sleep quality in people with Parkinson's disease. Participants are split into two groups: one receives OMT, the other a light t…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: New York Institute of Technology • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Can mindfulness together ease Parkinson's stress?
Symptom relief Recruiting nowThis study tests whether 8 weeks of mindfulness classes, taken together by people with Parkinson's and their family caregivers, can reduce negative emotions like stress, anxiety, and depression. About 200 Chinese patient-caregiver pairs will either take the classes or continue us…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Which anesthesia is better for Parkinson's battery surgery?
Symptom relief Recruiting nowThis study looks at two types of anesthesia for replacing the battery of a deep brain stimulator in people with Parkinson's disease. Researchers want to see which method—general anesthesia or regional anesthesia with sedation—provides better pain control and patient satisfaction …
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain mapping study could make Parkinson's treatment smarter
Knowledge-focused Recruiting nowThis study aims to understand how different brain circuits affect movement and thinking in people with Parkinson's disease who already have a deep brain stimulation (DBS) device. Researchers will measure brain activity patterns during rest and movement, and link them to motor and…
Matched conditions: PARKINSONS DISEASE
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC