PARKINSONS DISEASE
Clinical trials for PARKINSONS DISEASE explained in plain language.
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Ultrasound opens Blood-Brain barrier to deliver Parkinson's drug in first human test
Disease control Recruiting nowThis early-phase study tests whether a focused ultrasound technique can safely deliver a protein called GCase directly to a brain area affected by Parkinson's disease. The approach temporarily opens the blood-brain barrier to allow the drug to reach its target. The study involves…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated May 17, 2026 01:59 UTC
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Could a leg nerve graft to the brain ease Parkinson's and MSA?
Disease control Recruiting nowThis early study tests if implanting a small piece of the participant's own leg nerve into a key brain area is safe and feasible for people with early Parkinson's disease or Multiple System Atrophy (MSA). Seven people will take part; four will get the nerve graft and three will h…
Matched conditions: PARKINSONS DISEASE
Phase: PHASE1 • Sponsor: Craig van Horne, MD, PhD • Aim: Disease control
Last updated May 17, 2026 01:59 UTC
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New drug targets Parkinson's protein in Early-Stage trial
Disease control Recruiting nowThis study tests an experimental drug called ALN-SNCA in 46 people with early Parkinson's disease. The drug is given as a single injection into the spinal fluid to see if it is safe and can lower a harmful protein called alpha-synuclein. The goal is to find a treatment that slows…
Matched conditions: PARKINSONS DISEASE
Phase: PHASE1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated May 17, 2026 01:47 UTC
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New registry to track ultrasound brain surgery for Parkinson's tremors
Disease control Recruiting nowThis study tracks people with advanced Parkinson's disease who have a procedure called Exablate pallidotomy. The procedure uses focused ultrasound to target a small area in the brain to reduce medication-resistant motor complications like tremors and stiffness. Researchers will f…
Matched conditions: PARKINSONS DISEASE
Sponsor: InSightec • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Which anesthesia is better for Parkinson's battery surgery?
Symptom relief Recruiting nowThis study looks at two ways to manage pain during battery replacement surgery for deep brain stimulators in people with Parkinson's disease. One method uses general anesthesia (you are fully asleep), and the other uses regional anesthesia (you are awake but numb). The goal is to…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated May 17, 2026 01:47 UTC
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Mindfulness for two: new study aims to ease Parkinson's stress on patients and caregivers
Symptom relief Recruiting nowThis study tests whether an 8-week mindfulness program for people with Parkinson's disease and their family caregivers can reduce negative emotions and improve their relationship. About 200 Chinese patient-caregiver pairs will either take the mindfulness classes or continue usual…
Matched conditions: PARKINSONS DISEASE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Brain wiring study aims to sharpen deep brain stimulation for Parkinson's
Knowledge-focused Recruiting nowThis study looks at how different brain circuits are linked to movement and thinking in people with Parkinson's disease who already have a deep brain stimulation (DBS) device. Researchers will measure brain activity patterns during rest and movement, and connect them to standard …
Matched conditions: PARKINSONS DISEASE
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC