PALB2 GENE MUTATION
Clinical trials for PALB2 GENE MUTATION explained in plain language.
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Targeted pill trial offers hope for tough cancers with genetic flaw
Disease control OngoingThis study is testing an oral medication called talazoparib for people with advanced cancers that have spread, returned, or stopped responding to standard treatments. It is specifically for patients whose cancers have certain genetic changes in the BRCA pathway (like BRCA1, BRCA2…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope pill targets weakness in advanced breast cancer
Disease control OngoingThis study is testing whether a pill called olaparib can help control metastatic breast cancer that has spread in the body. It is for patients whose cancer has a specific weakness—a mutation in certain genes that help repair damaged DNA. The goal is to see if targeting this weakn…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Mar 09, 2026 14:23 UTC
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Targeted prostate cancer trial for hispanic and black men withdrawn before start
Disease control TerminatedThis study aimed to test a combination of two drugs, niraparib and abiraterone, plus a steroid, in men with newly diagnosed, advanced prostate cancer that had spread and had specific genetic changes. It specifically sought Hispanic/Latino and non-Hispanic Black participants to se…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE2 • Sponsor: Qian Qin • Aim: Disease control
Last updated Mar 09, 2026 14:23 UTC
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Cancer center hunts for early clues to stop deadly pancreatic tumors
Knowledge-focused OngoingThis study aims to create a large database of patient information to find better ways to detect pancreatic cancer early, when it's most treatable. It involves 317 adults at Moffitt Cancer Center who have pancreatic cysts, a strong family history of pancreatic cancer, or other ris…
Matched conditions: PALB2 GENE MUTATION
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Researchers test best way to deliver scary genetic news
Knowledge-focused TerminatedThis study aims to find the best way to help women understand their genetic cancer risk with less stress. It compares watching an online educational video alone to combining it with phone counseling sessions. The goal is to see which method helps participants feel less distressed…
Matched conditions: PALB2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC