PALB2 GENE MUTATION
Clinical trials for PALB2 GENE MUTATION explained in plain language.
Never miss a new study
Get alerted when new PALB2 GENE MUTATION trials appear
Sign up with your email to follow new studies for PALB2 GENE MUTATION, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
New combo therapy targets Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage trial tests a combination of two drugs, niraparib and irinotecan, in people with advanced solid tumors that have mutations in DNA repair genes like BRCA, ATM, or PALB2. The main goal is to find a safe dose and understand side effects. About 24 adults with cancers…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 17, 2026 04:14 UTC
-
New pill combo targets hard-to-treat inherited cancers
Disease control Recruiting nowThis early-stage trial tests a combination of two oral drugs (olaparib and ASTX727) in adults with advanced solid tumors that have specific gene mutations (BRCA1, BRCA2, PALB2, ATM, or CHEK2). The main goals are to find the safest dose and to see if the drugs can shrink tumors. A…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE1 • Sponsor: Pamela Munster • Aim: Disease control
Last updated May 17, 2026 04:12 UTC
-
New hope for pancreatic cancer: targeted combo trial for BRCA/PALB2 patients
Disease control Recruiting nowThis study tests a new combination of chemotherapy drugs (NABPLAGEM) against the standard combo for people with advanced pancreatic cancer that has a BRCA1/2 or PALB2 gene mutation. The goal is to see if the new combo works better at shrinking tumors and helping people live longe…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE2, PHASE3 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
-
Stem cell combo trial aims to outsmart Drug-Resistant cancers
Disease control Recruiting nowThis early-phase study tests a new treatment for people with metastatic pancreatic or breast cancer that has stopped responding to standard therapies. The treatment combines two chemotherapy drugs with high-dose vitamins and a stem cell transplant to help the body recover. The ma…
Matched conditions: PALB2 GENE MUTATION
Phase: PHASE1 • Sponsor: General Oncology, Inc. • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
-
New scan may spot hidden prostate cancer spread in men with BRCA and other gene mutations
Diagnosis Recruiting nowThis study aims to see if a type of PET-CT scan called FCH-PET-CT is better than standard scans (bone scan and MRI/CT) at finding cancer that has spread outside the pelvis in men with prostate cancer who have certain inherited gene mutations (like BRCA). About 50 men with these m…
Matched conditions: PALB2 GENE MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Diagnosis
Last updated May 17, 2026 04:16 UTC
-
Can digital tools make cancer genetic counseling more effective?
Knowledge-focused Recruiting nowThis study looks at two new approaches to cancer genetic counseling. The first helps healthcare providers reach out to family members who may have inherited a cancer-related gene change, making it easier for them to get tested. The second uses an online portal to keep patients an…
Matched conditions: PALB2 GENE MUTATION
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC