OUTPATIENT
Clinical trials for OUTPATIENT explained in plain language.
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Higher antidepressant dose may be risky for seniors with kidney disease
Knowledge-focused CompletedThis study looked at over 12,000 older adults (65+) with low kidney function to see if starting a higher dose (10 mg/day) of the antidepressant escitalopram is riskier than a lower dose (5 mg/day). The goal was to compare rates of hospitalization, emergency visits, or death withi…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 17, 2026 03:14 UTC
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Higher antidepressant dose may pose risks for seniors with weak kidneys
Knowledge-focused CompletedThis study looked at over 7,000 older adults (65+) with reduced kidney function to see if starting a higher dose (20 mg/day) of the antidepressant citalopram is riskier than a lower dose (10 mg/day). Researchers checked for hospital visits, emergency department visits, or death w…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Antidepressant dose safety checked in seniors with kidney disease
Knowledge-focused CompletedThis study reviewed health records of nearly 7,000 older adults (age 66+) with low kidney function to see if starting a higher dose (50 mg/day) of the antidepressant sertraline was riskier than a lower dose (25 mg/day). The researchers looked at whether people had to go to the ho…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC