OSTEOGENESIS IMPERFECTA, TYPE I
Clinical trials for OSTEOGENESIS IMPERFECTA, TYPE I explained in plain language.
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New drug aims to strengthen bones in kids with rare brittle bone disease
Disease control OngoingThis phase 3 study tests setrusumab, a monthly IV infusion, in 6 Japanese children with osteogenesis imperfecta (types I, III, or IV), a condition that causes fragile bones and frequent fractures. The main goal is to see if the drug lowers the number of fractures, including spine…
Matched conditions: OSTEOGENESIS IMPERFECTA, TYPE I
Phase: PHASE3 • Sponsor: Ultragenyx Pharmaceutical Inc • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New drug aims to slash fractures in brittle bone disease
Disease control OngoingThis study tests a medicine called setrusumab in people with osteogenesis imperfecta (brittle bone disease). The goal is to see if it can lower the number of bone fractures. About 183 participants with types I, III, or IV of the disease who have had recent fractures will receive …
Matched conditions: OSTEOGENESIS IMPERFECTA, TYPE I
Phase: PHASE2, PHASE3 • Sponsor: Ultragenyx Pharmaceutical Inc • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New drug aims to cut fractures in kids with brittle bones
Disease control OngoingThis study tests a new medicine called setrusumab against standard bone-strengthening drugs (bisphosphonates) in children aged 2 to under 7 with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. The goal is to see if setrusumab can lower the number of bone break…
Matched conditions: OSTEOGENESIS IMPERFECTA, TYPE I
Phase: PHASE3 • Sponsor: Ultragenyx Pharmaceutical Inc • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC