New drug aims to cut fractures in kids with brittle bones

NCT ID NCT06636071

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study tests a drug called setrusumab in Japanese children with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. The goal is to see if it lowers the number of bone fractures, including spine fractures. Participants must have had at least one fracture in the past year and have a confirmed genetic cause.

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Contacts and locations

Locations

  • Keio University Hospital

    Tokyo, Japan

  • Osaka Metropolitan University Hospital

    Osaka, Japan

  • Osaka University Hospital

    Osaka, Japan

Conditions

Explore the condition pages connected to this study.