OSTEOGENESIS IMPERFECTA (OI)
Clinical trials for OSTEOGENESIS IMPERFECTA (OI) explained in plain language.
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New shot aims to toughen fragile bones in rare disease
Disease control Recruiting nowThis phase 2 trial tests a drug called AGA2115 in 48 Chinese adults and adolescents with osteogenesis imperfecta (types I, III, IV), a condition that makes bones brittle. Participants receive one of three dose schedules by injection under the skin. The study checks for side effec…
Matched conditions: OSTEOGENESIS IMPERFECTA (OI)
Phase: PHASE2 • Sponsor: Angitia Biopharmaceuticals Guangzhou Limited • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New shot aims to fortify fragile bones in brittle bone disease trial
Disease control Recruiting nowThis study tests a drug called AGA2115 in 80 adults with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. Participants receive either the drug or a placebo as a shot under the skin. The main goal is to see if the drug increases bone density in the spine after 1…
Matched conditions: OSTEOGENESIS IMPERFECTA (OI)
Phase: PHASE2 • Sponsor: Angitia Incorporated Limited • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Brittle bones, fragile hearts? new study investigates cardiac risks in OI
Knowledge-focused Recruiting nowThis study is observing 40 people with osteogenesis imperfecta (brittle bone disease) to see how often heart problems occur. Researchers will use standard heart tests like echocardiograms to check for issues. The goal is to create better screening guidelines to catch heart proble…
Matched conditions: OSTEOGENESIS IMPERFECTA (OI)
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC