OSA

This large, completed Phase 3 study tested whether a daily pill called AD109 could help control obstructive sleep apnea in adults who cannot or will not use standard CPAP machines. For one year, 660 participants with moderate sleep apnea took either the active pill or a placebo t…

This study tested a new pill called AD109 to see if it can help control obstructive sleep apnea. It involved 646 adults with moderate sleep apnea who cannot or will not use standard CPAP machines. Participants took either the pill or a placebo for six months to measure changes in…

This study aimed to understand how two existing drugs, atomoxetine and oxybutynin, work together to improve obstructive sleep apnea. Researchers measured how the drugs affected specific throat muscles in 27 people with the condition during sleep. The goal was to learn the biologi…

This study tested a personalized exercise program, done partly at home and partly at a clinic, for people with chronic breathing problems like COPD or sleep apnea, and for people recovering from COVID-19. Researchers wanted to see if this 18-session program could help with common…

This small, completed study tested whether a single dose of the sleep medication lemborexant could help people with moderate-to-severe obstructive sleep apnea (OSA). Ten adults with a specific type of OSA (where they wake up easily from breathing struggles) took either the drug o…

This study used ultrasound imaging to examine how the diaphragm (the main breathing muscle) functions in people with obstructive sleep apnea. Researchers measured 60 patients' diaphragm movements to see if they relate to how severe their sleep apnea is. The goal was to better und…