OSA
Clinical trials for OSA explained in plain language.
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New daily pill could ease sleep apnea for people with obesity
Disease control OngoingThis phase 3 trial tests a once-daily medication called orforglipron in 600 adults with moderate-to-severe obstructive sleep apnea (OSA) who are also overweight or have obesity. The study has two parts: one for people who cannot or will not use a CPAP machine, and another for tho…
Matched conditions: OSA
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Could a leg pump boost brain health in sleep apnea?
Knowledge-focused ENROLLING_BY_INVITATIONThis early study at Mayo Clinic tests whether using an automated leg massage device (Neuroglide) each night for one month can improve the brain's waste-clearing system in people aged 50+ with obstructive sleep apnea. Researchers will measure changes in blood markers linked to bra…
Matched conditions: OSA
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 05:07 UTC
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New airway device study pulled before enrolling a single patient
Knowledge-focused TerminatedThis study was designed to see if a new type of breathing tube could help prevent dangerously low oxygen levels during anesthesia in people at high risk, such as those with obesity or sleep apnea. It planned to compare the new device with standard tubes in adults having surgery a…
Matched conditions: OSA
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 17, 2026 05:05 UTC