ORTHOPEDIC SURGERY
Clinical trials for ORTHOPEDIC SURGERY explained in plain language.
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Sleep hormone trial aims to stop Post-Surgery confusion in elderly
Prevention CompletedThis study tested whether melatonin, a natural sleep-regulating hormone, can prevent postoperative delirium—a common and serious state of confusion—in older adults having emergency surgery for broken hips or knees. Researchers gave 357 patients aged 70+ either melatonin or a plac…
Matched conditions: ORTHOPEDIC SURGERY
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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Which common pain pill works best before surgery?
Symptom relief CompletedThis study compared two similar pain medications, pregabalin and gabapentin, given to patients before leg surgery. Researchers wanted to see which drug provided longer-lasting pain relief after surgery and reduced the need for strong opioid painkillers. The study involved 142 adu…
Matched conditions: ORTHOPEDIC SURGERY
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated Apr 02, 2026 05:12 UTC