ORTHOPEDIC SURGERY
Clinical trials for ORTHOPEDIC SURGERY explained in plain language.
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Sleep hormone may shield seniors from Post-Surgery brain fog
Prevention CompletedThis study tested whether taking melatonin, a natural sleep hormone, before and after surgery could prevent delirium (sudden confusion) in older adults with broken leg bones. About 357 patients aged 70 and older received either melatonin or a placebo pill nightly from before surg…
Matched conditions: ORTHOPEDIC SURGERY
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated May 17, 2026 12:46 UTC
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New program eases depression and anxiety in seniors facing joint replacement
Symptom relief CompletedThis study tested a program that combines counseling and medication adjustments to reduce depression and anxiety in adults aged 60 and older who were scheduled for hip or knee replacement surgery. 116 participants were split into two groups: one received the program plus usual ca…
Matched conditions: ORTHOPEDIC SURGERY
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 17, 2026 12:54 UTC
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Which painkiller wins? study tests pregabalin vs gabapentin after surgery
Symptom relief CompletedThis study looked at 142 adults aged 20-60 who had lower limb surgery with spinal anesthesia. Researchers compared two pain medicines, pregabalin and gabapentin, given before surgery to see which one worked better. The goal was to find which drug reduced pain more and kept pain a…
Matched conditions: ORTHOPEDIC SURGERY
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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Massage may speed knee recovery after replacement
Symptom relief CompletedThis study tested whether adding a specific massage technique (manual lymphatic drainage) to standard physical therapy helps people regain knee movement faster after knee replacement surgery. The study involved 44 adults who had knee replacement and compared those who received th…
Matched conditions: ORTHOPEDIC SURGERY
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Symptom relief
Last updated May 04, 2026 16:19 UTC