OPIOID OVERDOSE
Clinical trials for OPIOID OVERDOSE explained in plain language.
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App trains citizens to save lives from opioid overdoses
Prevention CompletedThis study tested a new system called the Opioid Rapid Response System (ORRS) that uses a smartphone app to train and alert citizens to respond to opioid overdoses with the life-saving drug naloxone. Over 770 adults from participating communities took part in a national trial to …
Matched conditions: OPIOID OVERDOSE
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Prevention
Last updated May 12, 2026 13:40 UTC
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New study tests for hidden danger in opioid overdoses
Knowledge-focused CompletedThis study looked at 75 emergency room patients who had a non-fatal opioid overdose. Researchers measured the amount of xylazine, a veterinary sedative, in their blood and tested urine drug strips to see how well they detect xylazine. The goal was to better understand and identif…
Matched conditions: OPIOID OVERDOSE
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated May 17, 2026 08:01 UTC
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Data tool predicts overdose hotspots to save lives
Knowledge-focused CompletedThis study tested a new tool that uses data to predict where opioid overdoses are most likely to happen. Researchers worked with 39 cities and towns in Rhode Island to see if sending prevention resources to high-risk neighborhoods could reduce overdose deaths. The goal is to help…
Matched conditions: OPIOID OVERDOSE
Phase: NA • Sponsor: Brown University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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New naloxone nasal spray put to the test in healthy volunteers
Knowledge-focused CompletedThis study tested a new device (AP003) that delivers naloxone as a nasal spray to reverse opioid overdoses. Twenty-four healthy adults received multiple doses to see how the drug moves through the body and to check for side effects. The goal was to compare the new spray with the …
Matched conditions: OPIOID OVERDOSE
Phase: PHASE1 • Sponsor: Emergent BioSolutions • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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New shot for opioid overdose tested in healthy volunteers
Knowledge-focused CompletedThis early-stage study tested how a drug called nalmefene behaves in the body when given as a shot into muscle or directly into a vein. Thirteen healthy adults received small doses to compare the two methods. The goal was to gather information that could help develop faster-actin…
Matched conditions: OPIOID OVERDOSE
Phase: PHASE1 • Sponsor: Purdue Pharma LP • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:36 UTC